ENDOTHERANOSTICS RESEARCH CHALLENGES

Endoluminal Navigation

 

STATE OF THE ART

Limited steering capability

Heuristic design methods

Operation in non-realistic environments

INNOVATION

Fusing function with structure

Simulation-based integrative design

In-situ instrument deployment

BREAKTHROUGH

Design of frictionless, shape-conforming robot integrating sensor and microsurgical tools with embodied AI for navigation and controlled real-time adaptation in constrictive and dynamic environments

IN-SITU HISTOPATHOLOGY

 

STATE OF THE ART

Polyp detection with no staging

Time-consuming tissue assessment

Limited probe manoeuvrability

INNOVATION

Sensor analytics and machine learning

Large area to be covered by sensing

Probe fabrication and miniaturisation

BREAKTHROUGH

Intelligent and multimodal sensing including wide-field multispectral imaging, photoacoustic endomicroscopy and all-optical ultrasound imaging for in-vivo in-situ detection and characterisation of tissue properties

SUPERVISED AUTONOMY

 

STATE OF THE ART

Teleoperation with passive compliance

Virtual fixtures in rigid environments

No active control of soft robot and capsule

INNOVATION

Intuitive shared control at multiple scales

AI methods to extract environment data

Visual control for navigation and inspection

BREAKTHROUGH

Human‒machine cooperation with perceptional feedback for model-based and data-driven control of endoluminal navigation and microsurgical tasks in tight/soft environments

MICROROBOTIC SURGERY 

 

STATE OF THE ART

Passive tools with no tissue handling

Monopolar high-frequency probes

No perceptional feedback

INNOVATION

Super-flex high-strength microrobot

Foldable jaws for tissue handling

Real-time intraoperative manipulation

BREAKTHROUGH

Microsurgical robot with bimanual tissue manipulation based on a unique no-energy miniaturised continuum arm design for high-precision sub-mm oncologically-safe excision of polyps in the deforming colon